rac-2-Hydroxy-2,8-dimethyl-4-morpho­linoethyl-1-thia-4-aza­spiro­[4.5]decan-3-one

The title compound, C(16)H(28)N(2)O(3)S, is dimerized by inversion symmetry-related inter­molecular O—H⋯N hydrogen bonding, forming an R (2) (2)(16) motif. The dimers are also linked through inter­molecular C—H⋯O hydrogen bonding. The compound is chiral with a stereogenic centre located in the thia­...

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Detalles Bibliográficos
Autores principales: Akkurt, Mehmet, Yalçın, Şerife Pınar, Klip, Nalan Terzioğlu, Büyükgüngör, Orhan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962193/
https://www.ncbi.nlm.nih.gov/pubmed/21203274
http://dx.doi.org/10.1107/S1600536808022447
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author Akkurt, Mehmet
Yalçın, Şerife Pınar
Klip, Nalan Terzioğlu
Büyükgüngör, Orhan
author_facet Akkurt, Mehmet
Yalçın, Şerife Pınar
Klip, Nalan Terzioğlu
Büyükgüngör, Orhan
author_sort Akkurt, Mehmet
collection PubMed
description The title compound, C(16)H(28)N(2)O(3)S, is dimerized by inversion symmetry-related inter­molecular O—H⋯N hydrogen bonding, forming an R (2) (2)(16) motif. The dimers are also linked through inter­molecular C—H⋯O hydrogen bonding. The compound is chiral with a stereogenic centre located in the thia­zole ring, but in the crystal structure it forms a racemate. The thia­zole ring has an envelope conformation, while the cyclo­hexane and morpholine rings adopt chair conformations.
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spelling pubmed-29621932010-12-30 rac-2-Hydroxy-2,8-dimethyl-4-morpho­linoethyl-1-thia-4-aza­spiro­[4.5]decan-3-one Akkurt, Mehmet Yalçın, Şerife Pınar Klip, Nalan Terzioğlu Büyükgüngör, Orhan Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(16)H(28)N(2)O(3)S, is dimerized by inversion symmetry-related inter­molecular O—H⋯N hydrogen bonding, forming an R (2) (2)(16) motif. The dimers are also linked through inter­molecular C—H⋯O hydrogen bonding. The compound is chiral with a stereogenic centre located in the thia­zole ring, but in the crystal structure it forms a racemate. The thia­zole ring has an envelope conformation, while the cyclo­hexane and morpholine rings adopt chair conformations. International Union of Crystallography 2008-07-23 /pmc/articles/PMC2962193/ /pubmed/21203274 http://dx.doi.org/10.1107/S1600536808022447 Text en © Akkurt et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Akkurt, Mehmet
Yalçın, Şerife Pınar
Klip, Nalan Terzioğlu
Büyükgüngör, Orhan
rac-2-Hydroxy-2,8-dimethyl-4-morpho­linoethyl-1-thia-4-aza­spiro­[4.5]decan-3-one
title rac-2-Hydroxy-2,8-dimethyl-4-morpho­linoethyl-1-thia-4-aza­spiro­[4.5]decan-3-one
title_full rac-2-Hydroxy-2,8-dimethyl-4-morpho­linoethyl-1-thia-4-aza­spiro­[4.5]decan-3-one
title_fullStr rac-2-Hydroxy-2,8-dimethyl-4-morpho­linoethyl-1-thia-4-aza­spiro­[4.5]decan-3-one
title_full_unstemmed rac-2-Hydroxy-2,8-dimethyl-4-morpho­linoethyl-1-thia-4-aza­spiro­[4.5]decan-3-one
title_short rac-2-Hydroxy-2,8-dimethyl-4-morpho­linoethyl-1-thia-4-aza­spiro­[4.5]decan-3-one
title_sort rac-2-hydroxy-2,8-dimethyl-4-morpho­linoethyl-1-thia-4-aza­spiro­[4.5]decan-3-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962193/
https://www.ncbi.nlm.nih.gov/pubmed/21203274
http://dx.doi.org/10.1107/S1600536808022447
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AT buyukgungororhan rac2hydroxy28dimethyl4morpholinoethyl1thia4azaspiro45decan3one

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