(R)-(+)-3-Hydr­oxy-2-methoxy­carbonyl-8-methyl-8-azoniabicyclo­[3.2.1]octane l-bitartrate

(RS)-(±)-2-Methoxy­carbonyl-3-tropinone is an important inter­mediate for the preparation of cocaine and its derivatives. The molecule in the title compound, C(10)H(16)NO(3) (+)·C(4)H(5)O(6) (−), is present as the enol tautomer. The six-membered ring adopts a half boat conformation, and the five-mem...

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Detalles Bibliográficos
Autores principales: Yu, Jian-Bing, Chen, Shuang-Wei, Zheng, Guo-Rong, Dai, Li-Yan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962227/
https://www.ncbi.nlm.nih.gov/pubmed/21203339
http://dx.doi.org/10.1107/S1600536808023532
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author Yu, Jian-Bing
Chen, Shuang-Wei
Zheng, Guo-Rong
Dai, Li-Yan
author_facet Yu, Jian-Bing
Chen, Shuang-Wei
Zheng, Guo-Rong
Dai, Li-Yan
author_sort Yu, Jian-Bing
collection PubMed
description (RS)-(±)-2-Methoxy­carbonyl-3-tropinone is an important inter­mediate for the preparation of cocaine and its derivatives. The molecule in the title compound, C(10)H(16)NO(3) (+)·C(4)H(5)O(6) (−), is present as the enol tautomer. The six-membered ring adopts a half boat conformation, and the five-membered ring a slightly distorted envelope conformation. There are intra- and inter­molecular hydrogen bonds involving the hydroxyl, carboxyl groups and quaternary ammonium groups.
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spelling pubmed-29622272010-12-30 (R)-(+)-3-Hydr­oxy-2-methoxy­carbonyl-8-methyl-8-azoniabicyclo­[3.2.1]octane l-bitartrate Yu, Jian-Bing Chen, Shuang-Wei Zheng, Guo-Rong Dai, Li-Yan Acta Crystallogr Sect E Struct Rep Online Organic Papers (RS)-(±)-2-Methoxy­carbonyl-3-tropinone is an important inter­mediate for the preparation of cocaine and its derivatives. The molecule in the title compound, C(10)H(16)NO(3) (+)·C(4)H(5)O(6) (−), is present as the enol tautomer. The six-membered ring adopts a half boat conformation, and the five-membered ring a slightly distorted envelope conformation. There are intra- and inter­molecular hydrogen bonds involving the hydroxyl, carboxyl groups and quaternary ammonium groups. International Union of Crystallography 2008-07-31 /pmc/articles/PMC2962227/ /pubmed/21203339 http://dx.doi.org/10.1107/S1600536808023532 Text en © Yu et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Yu, Jian-Bing
Chen, Shuang-Wei
Zheng, Guo-Rong
Dai, Li-Yan
(R)-(+)-3-Hydr­oxy-2-methoxy­carbonyl-8-methyl-8-azoniabicyclo­[3.2.1]octane l-bitartrate
title (R)-(+)-3-Hydr­oxy-2-methoxy­carbonyl-8-methyl-8-azoniabicyclo­[3.2.1]octane l-bitartrate
title_full (R)-(+)-3-Hydr­oxy-2-methoxy­carbonyl-8-methyl-8-azoniabicyclo­[3.2.1]octane l-bitartrate
title_fullStr (R)-(+)-3-Hydr­oxy-2-methoxy­carbonyl-8-methyl-8-azoniabicyclo­[3.2.1]octane l-bitartrate
title_full_unstemmed (R)-(+)-3-Hydr­oxy-2-methoxy­carbonyl-8-methyl-8-azoniabicyclo­[3.2.1]octane l-bitartrate
title_short (R)-(+)-3-Hydr­oxy-2-methoxy­carbonyl-8-methyl-8-azoniabicyclo­[3.2.1]octane l-bitartrate
title_sort (r)-(+)-3-hydr­oxy-2-methoxy­carbonyl-8-methyl-8-azoniabicyclo­[3.2.1]octane l-bitartrate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962227/
https://www.ncbi.nlm.nih.gov/pubmed/21203339
http://dx.doi.org/10.1107/S1600536808023532
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