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Structural and Functional Investigations of Matrilin-1 A-domains Reveal Insights into Their Role in Cartilage ECM Assembly

Matrilin-1 is expressed predominantly in cartilage and co-localizes with matrilin-3 with which it can form hetero-oligomers. We recently described novel structural and functional features of the matrilin-3 A-domain (M3A) and demonstrated that it bound with high affinity to type II and IX collagens....

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Detalles Bibliográficos
Autores principales:	Fresquet, Maryline, Jowitt, Thomas A., Stephen, Louise A., Ylöstalo, Joni, Briggs, Michael D.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2010
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962504/ https://www.ncbi.nlm.nih.gov/pubmed/20729554 http://dx.doi.org/10.1074/jbc.M110.154443

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