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Prion protein and Aβ-related synaptic toxicity impairment

Alzheimer's disease (AD), the most common neurodegenerative disorder, goes along with extracellular amyloid-β (Aβ) deposits. The cognitive decline observed during AD progression correlates with damaged spines, dendrites and synapses in hippocampus and cortex. Numerous studies have shown that Aβ...

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Detalles Bibliográficos
Autores principales:	Calella, Anna Maria, Farinelli, Mélissa, Nuvolone, Mario, Mirante, Osvaldo, Moos, Rita, Falsig, Jeppe, Mansuy, Isabelle M, Aguzzi, Adriano
Formato:	Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2010
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962809/ https://www.ncbi.nlm.nih.gov/pubmed/20665634 http://dx.doi.org/10.1002/emmm.201000082

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