REEMERGENCE OF POSITIVE SYMPTOMS OF SCHIZOPHRENIA DURING THE COURSE OF TREATMENT WITH RISPERIDONE

Thirty patients suffering from schizophrenia (diagnosed as per DSM-IV criteria), for more than 2 years and having predominant negative symptoms were started on risperidone (2-10 mg/day) and were followed up over a period of 16 weeks. The improvement was assessed using PANSS (Positive and Negative Sy...

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Detalles Bibliográficos
Autores principales: Bajaj, Priya, Nihalani, Nikhil, Shah, Nilesh, Desai, Neena, Shinde, Veena, Raut, Nivedita
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962850/
https://www.ncbi.nlm.nih.gov/pubmed/21455369
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author Bajaj, Priya
Nihalani, Nikhil
Shah, Nilesh
Desai, Neena
Shinde, Veena
Raut, Nivedita
author_facet Bajaj, Priya
Nihalani, Nikhil
Shah, Nilesh
Desai, Neena
Shinde, Veena
Raut, Nivedita
author_sort Bajaj, Priya
collection PubMed
description Thirty patients suffering from schizophrenia (diagnosed as per DSM-IV criteria), for more than 2 years and having predominant negative symptoms were started on risperidone (2-10 mg/day) and were followed up over a period of 16 weeks. The improvement was assessed using PANSS (Positive and Negative Syndrome Scale). During this 16 weeks follow up, it was interestingly noted that though there was a significant improvement in negative symptoms in all the patients, in 7 patients there was a reemergence of positive symptoms. Four patients had increase in rating on suspiciousness and hostility and two patients reported auditory hallucinations. One patient developed delusions and conceptual disorganization along with suspiciousness and hostility.
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spelling pubmed-29628502011-03-31 REEMERGENCE OF POSITIVE SYMPTOMS OF SCHIZOPHRENIA DURING THE COURSE OF TREATMENT WITH RISPERIDONE Bajaj, Priya Nihalani, Nikhil Shah, Nilesh Desai, Neena Shinde, Veena Raut, Nivedita Indian J Psychiatry Original Article Thirty patients suffering from schizophrenia (diagnosed as per DSM-IV criteria), for more than 2 years and having predominant negative symptoms were started on risperidone (2-10 mg/day) and were followed up over a period of 16 weeks. The improvement was assessed using PANSS (Positive and Negative Syndrome Scale). During this 16 weeks follow up, it was interestingly noted that though there was a significant improvement in negative symptoms in all the patients, in 7 patients there was a reemergence of positive symptoms. Four patients had increase in rating on suspiciousness and hostility and two patients reported auditory hallucinations. One patient developed delusions and conceptual disorganization along with suspiciousness and hostility. Medknow Publications 1999 /pmc/articles/PMC2962850/ /pubmed/21455369 Text en Copyright: © Indian Journal of Psychiatry http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Bajaj, Priya
Nihalani, Nikhil
Shah, Nilesh
Desai, Neena
Shinde, Veena
Raut, Nivedita
REEMERGENCE OF POSITIVE SYMPTOMS OF SCHIZOPHRENIA DURING THE COURSE OF TREATMENT WITH RISPERIDONE
title REEMERGENCE OF POSITIVE SYMPTOMS OF SCHIZOPHRENIA DURING THE COURSE OF TREATMENT WITH RISPERIDONE
title_full REEMERGENCE OF POSITIVE SYMPTOMS OF SCHIZOPHRENIA DURING THE COURSE OF TREATMENT WITH RISPERIDONE
title_fullStr REEMERGENCE OF POSITIVE SYMPTOMS OF SCHIZOPHRENIA DURING THE COURSE OF TREATMENT WITH RISPERIDONE
title_full_unstemmed REEMERGENCE OF POSITIVE SYMPTOMS OF SCHIZOPHRENIA DURING THE COURSE OF TREATMENT WITH RISPERIDONE
title_short REEMERGENCE OF POSITIVE SYMPTOMS OF SCHIZOPHRENIA DURING THE COURSE OF TREATMENT WITH RISPERIDONE
title_sort reemergence of positive symptoms of schizophrenia during the course of treatment with risperidone
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962850/
https://www.ncbi.nlm.nih.gov/pubmed/21455369
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