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Hodgkin's Lymphomas: A Tumor Recognized by Its Microenvironment
Thomas Hodgkin's and Samuel Wilks first recognized Hodgkin disease in the first half of the 19th century. Initially described as lymphogranulomatosis, it was later recognized to be a lymphoid neoplasm derived from B cells and was classified on the basis of its histopathological features. Hodgki...
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963118/ https://www.ncbi.nlm.nih.gov/pubmed/20981155 http://dx.doi.org/10.1155/2011/142395 |
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author | Montes-Moreno, S. |
author_facet | Montes-Moreno, S. |
author_sort | Montes-Moreno, S. |
collection | PubMed |
description | Thomas Hodgkin's and Samuel Wilks first recognized Hodgkin disease in the first half of the 19th century. Initially described as lymphogranulomatosis, it was later recognized to be a lymphoid neoplasm derived from B cells and was classified on the basis of its histopathological features. Hodgkin lymphomas are now regarded as encompassing two clearly defined entities according to the WHO classification: nodular lymphocyte-predominant Hodgkin Lymphoma (NLPHL) and classical Hodgkin Lymphoma (CHL). This paper focuses on the current knowledge about the biological features that characterize both NLPHL and CHL, highlighting those relevant to correct pathological diagnosis and those that might be associated with patient outcome. |
format | Text |
id | pubmed-2963118 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-29631182010-10-27 Hodgkin's Lymphomas: A Tumor Recognized by Its Microenvironment Montes-Moreno, S. Adv Hematol Review Article Thomas Hodgkin's and Samuel Wilks first recognized Hodgkin disease in the first half of the 19th century. Initially described as lymphogranulomatosis, it was later recognized to be a lymphoid neoplasm derived from B cells and was classified on the basis of its histopathological features. Hodgkin lymphomas are now regarded as encompassing two clearly defined entities according to the WHO classification: nodular lymphocyte-predominant Hodgkin Lymphoma (NLPHL) and classical Hodgkin Lymphoma (CHL). This paper focuses on the current knowledge about the biological features that characterize both NLPHL and CHL, highlighting those relevant to correct pathological diagnosis and those that might be associated with patient outcome. Hindawi Publishing Corporation 2011 2010-10-24 /pmc/articles/PMC2963118/ /pubmed/20981155 http://dx.doi.org/10.1155/2011/142395 Text en Copyright © 2011 S. Montes-Moreno. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Montes-Moreno, S. Hodgkin's Lymphomas: A Tumor Recognized by Its Microenvironment |
title | Hodgkin's Lymphomas: A Tumor Recognized by Its Microenvironment |
title_full | Hodgkin's Lymphomas: A Tumor Recognized by Its Microenvironment |
title_fullStr | Hodgkin's Lymphomas: A Tumor Recognized by Its Microenvironment |
title_full_unstemmed | Hodgkin's Lymphomas: A Tumor Recognized by Its Microenvironment |
title_short | Hodgkin's Lymphomas: A Tumor Recognized by Its Microenvironment |
title_sort | hodgkin's lymphomas: a tumor recognized by its microenvironment |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963118/ https://www.ncbi.nlm.nih.gov/pubmed/20981155 http://dx.doi.org/10.1155/2011/142395 |
work_keys_str_mv | AT montesmorenos hodgkinslymphomasatumorrecognizedbyitsmicroenvironment |