Synthesis and Splice-Redirecting Activity of Branched, Arginine-Rich Peptide Dendrimer Conjugates of Peptide Nucleic Acid Oligonucleotides

Arginine-rich cell-penetrating peptides have found excellent utility in cell and in vivo models for enhancement of delivery of attached charge-neutral PNA or PMO oligonucleotides. We report the synthesis of dendrimeric peptides containing 2- or 4-branched arms each having one or more R-Ahx-R motifs...

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Detalles Bibliográficos
Autores principales: Saleh, Amer F., Arzumanov, Andrey, Abes, Rachida, Owen, David, Lebleu, Bernard, Gait, Michael J.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963316/
https://www.ncbi.nlm.nih.gov/pubmed/20879728
http://dx.doi.org/10.1021/bc100275r

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963316/
https://www.ncbi.nlm.nih.gov/pubmed/20879728
http://dx.doi.org/10.1021/bc100275r

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