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AMP-activated Protein Kinase α2 Subunit Is Required for the Preservation of Hepatic Insulin Sensitivity by n-3 Polyunsaturated Fatty Acids

OBJECTIVE: The induction of obesity, dyslipidemia, and insulin resistance by high-fat diet in rodents can be prevented by n-3 long-chain polyunsaturated fatty acids (LC-PUFAs). We tested a hypothesis whether AMP-activated protein kinase (AMPK) has a role in the beneficial effects of n-3 LC-PUFAs. RE...

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Detalles Bibliográficos
Autores principales:	Jelenik, Tomas, Rossmeisl, Martin, Kuda, Ondrej, Jilkova, Zuzana Macek, Medrikova, Dasa, Kus, Vladimir, Hensler, Michal, Janovska, Petra, Miksik, Ivan, Baranowski, Marcin, Gorski, Jan, Hébrard, Sophie, Jensen, Thomas E., Flachs, Pavel, Hawley, Simon, Viollet, Benoit, Kopecky, Jan
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963531/ https://www.ncbi.nlm.nih.gov/pubmed/20693347 http://dx.doi.org/10.2337/db09-1716

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