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DsbA-L Alleviates Endoplasmic Reticulum Stress–Induced Adiponectin Downregulation

OBJECTIVE: Obesity impairs adiponectin expression, assembly, and secretion, yet the underlying mechanisms remain elusive. The aims of this study were 1) to determine the molecular mechanisms by which obesity impairs adiponectin multimerization and stability, and 2) to determine the potential role of...

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Detalles Bibliográficos
Autores principales: Zhou, Lijun, Liu, Meilian, Zhang, Jingjing, Chen, Hongzhi, Dong, Lily Q., Liu, Feng
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963539/
https://www.ncbi.nlm.nih.gov/pubmed/20699416
http://dx.doi.org/10.2337/db10-0412