Cargando…
Cannabinoid Receptor Stimulation Impairs Mitochondrial Biogenesis in Mouse White Adipose Tissue, Muscle, and Liver: The Role of eNOS, p38 MAPK, and AMPK Pathways
OBJECTIVE: Cannabinoid type 1 (CB1) receptor is involved in whole-body and cellular energy metabolism. We asked whether CB1 receptor stimulation was able to decrease mitochondrial biogenesis in different metabolically active tissues of obese high-fat diet (HFD)-fed mice. RESEARCH DESIGN AND METHODS:...
Autores principales: | Tedesco, Laura, Valerio, Alessandra, Dossena, Marta, Cardile, Annalisa, Ragni, Maurizio, Pagano, Claudio, Pagotto, Uberto, Carruba, Michele O., Vettor, Roberto, Nisoli, Enzo |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963541/ https://www.ncbi.nlm.nih.gov/pubmed/20739683 http://dx.doi.org/10.2337/db09-1881 |
Ejemplares similares
-
Cannabinoid Type 1 Receptor Blockade Promotes Mitochondrial Biogenesis Through Endothelial Nitric Oxide Synthase Expression in White Adipocytes
por: Tedesco, Laura, et al.
Publicado: (2008) -
An amino acid-defined diet impairs tumour growth in mice by promoting endoplasmic reticulum stress and mTOR inhibition
por: Ragni, Maurizio, et al.
Publicado: (2022) -
Manipulation of Dietary Amino Acids Prevents and Reverses Obesity in Mice Through Multiple Mechanisms That Modulate Energy Homeostasis
por: Ruocco, Chiara, et al.
Publicado: (2020) -
Novel indolic AMPK modulators induce vasodilatation through activation of the AMPK–eNOS–NO pathway
por: Sanz-Gómez, Marta, et al.
Publicado: (2022) -
A Special Amino-Acid Formula Tailored to Boosting Cell Respiration Prevents Mitochondrial Dysfunction and Oxidative Stress Caused by Doxorubicin in Mouse Cardiomyocytes
por: Tedesco, Laura, et al.
Publicado: (2020)