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Evaluation of A2BP1 as an Obesity Gene
OBJECTIVE: A genome-wide association study (GWAS) in Pima Indians (n = 413) identified variation in the ataxin-2 binding protein 1 gene (A2BP1) that was associated with percent body fat. On the basis of this association and the obese phenotype of ataxin-2 knockout mice, A2BP1 was genetically and fun...
Autores principales: | Ma, Lijun, Hanson, Robert L., Traurig, Michael T., Muller, Yunhua L., Kaur, Bakhshish P., Perez, Jessica M., Meyre, David, Fu, Mao, Körner, Antje, Franks, Paul W., Kiess, Wieland, Kobes, Sayuko, Knowler, William C., Kovacs, Peter, Froguel, Philippe, Shuldiner, Alan R., Bogardus, Clifton, Baier, Leslie J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963542/ https://www.ncbi.nlm.nih.gov/pubmed/20724578 http://dx.doi.org/10.2337/db09-1604 |
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