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TNF-α Signals Through PKCζ/NF-κB to Alter the Tight Junction Complex and Increase Retinal Endothelial Cell Permeability

OBJECTIVE: Tumor necrosis factor-α (TNF-α) and interleukin-1 beta (IL-1β) are elevated in the vitreous of diabetic patients and in retinas of diabetic rats associated with increased retinal vascular permeability. However, the molecular mechanisms underlying retinal vascular permeability induced by t...

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Detalles Bibliográficos
Autores principales:	Aveleira, Célia A., Lin, Cheng-Mao, Abcouwer, Steven F., Ambrósio, António F., Antonetti, David A.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Pathophysiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963546/ https://www.ncbi.nlm.nih.gov/pubmed/20693346 http://dx.doi.org/10.2337/db09-1606

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