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Expression of Human Chemerin Induces Insulin Resistance in the Skeletal Muscle but Does Not Affect Weight, Lipid Levels, and Atherosclerosis in LDL Receptor Knockout Mice on High-Fat Diet
OBJECTIVE: Chemerin is a recently discovered hepatoadipokine that regulates adipocyte differentiation as well as chemotaxis and activation of dendritic cells and macrophages. Chemerin was reported to modulate insulin sensitivity in adipocytes and skeletal muscle cells in vitro and to exacerbate gluc...
Autores principales: | Becker, Melanie, Rabe, Katja, Lebherz, Corinna, Zugwurst, Julia, Göke, Burkhard, Parhofer, Klaus G., Lehrke, Michael, Broedl, Uli C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963549/ https://www.ncbi.nlm.nih.gov/pubmed/20724582 http://dx.doi.org/10.2337/db10-0362 |
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