Enhanced Levels of microRNA-125b in Vascular Smooth Muscle Cells of Diabetic db/db Mice Lead to Increased Inflammatory Gene Expression by Targeting the Histone Methyltransferase Suv39h1

OBJECTIVE: Diabetes remains a major risk factor for vascular complications that seem to persist even after achieving glycemic control, possibly due to “metabolic memory.” Using cultured vascular smooth muscle cells (MVSMC) from type 2 diabetic db/db mice, we recently showed that decreased promoter o...

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Detalles Bibliográficos
Autores principales: Villeneuve, Louisa M., Kato, Mitsuo, Reddy, Marpadga A., Wang, Mei, Lanting, Linda, Natarajan, Rama
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963550/
https://www.ncbi.nlm.nih.gov/pubmed/20699419
http://dx.doi.org/10.2337/db10-0208

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