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Altered Lung Morphogenesis, Epithelial Cell Differentiation and Mechanics in Mice Deficient in the Wnt/β-Catenin Antagonist Chibby

The canonical Wnt/β-catenin pathway plays crucial roles in various aspects of lung morphogenesis and regeneration/repair. Here, we examined the lung phenotype and function in mice lacking the Wnt/β-catenin antagonist Chibby (Cby). In support of its inhibitory role in canonical Wnt signaling, express...

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Detalles Bibliográficos
Autores principales: Love, Damon, Li, Feng-Qian, Burke, Michael C., Cyge, Benjamin, Ohmitsu, Masao, Cabello, Jeffrey, Larson, Janet E., Brody, Steven L., Cohen, J. Craig, Takemaru, Ken-Ichi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963606/
https://www.ncbi.nlm.nih.gov/pubmed/21049041
http://dx.doi.org/10.1371/journal.pone.0013600