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Germline Met Mutations in Mice Reveal Mutation- and Background-Associated Differences in Tumor Profiles

BACKGROUND: The receptor tyrosine kinase Met is involved in the progression and metastasis of numerous human cancers. Although overexpression and autocrine activation of the Met signaling pathway are commonly found in human cancers, mutational activation of Met has been observed in small cell and no...

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Detalles Bibliográficos
Autores principales: Graveel, Carrie R., DeGroot, Jack D., Sigler, Robert E., Vande Woude, George F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963642/
https://www.ncbi.nlm.nih.gov/pubmed/21049054
http://dx.doi.org/10.1371/journal.pone.0013586

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