Cargando…

Recombinant adenovirus IL-24-Bax promotes apoptosis of hepatocellular carcinoma cells in vitro and in vivo

Gene therapy promises to become an alternative choice for the treatment of hepatic cancer. In many cancers, the delivery of chimeric proteins by adenovirus vector has been reported to induce apoptosis. This study was performed to evaluate whether the recombinant adenovirus interleukin (IL)-24-Bax ca...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, J, Shi, L, Zhang, X, Kang, X, Wen, Y, Qian, H, Zhou, Y, Xu, W, Zhang, Y, Wu, M, Yin, Z
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963730/ https://www.ncbi.nlm.nih.gov/pubmed/20596089 http://dx.doi.org/10.1038/cgt.2010.34

Ejemplares similares

Oncolytic adenovirus armed with IL-24 Inhibits the growth of breast cancer in vitro and in vivo
por: Zhu, Wei, et al.
Publicado: (2012)

CD123 targeting oncolytic adenoviruses suppress acute myeloid leukemia cell proliferation in vitro and in vivo
por: Li, G, et al.
Publicado: (2014)

Histone acetyltransferase PCAF accelerates apoptosis by repressing a GLI1/BCL2/BAX axis in hepatocellular carcinoma
por: Gai, X, et al.
Publicado: (2015)

A conditionally replicating adenovirus expressing IL-24 acts synergistically with temozolomide to enhance apoptosis in melanoma cells in vitro
por: Liang, Zhen, et al.
Publicado: (2017)

Caspase-3 feedback loop enhances Bid-induced AIF/endoG and Bak activation in Bax and p53-independent manner
por: Guo, W, et al.
Publicado: (2015)

Interferon-α enhances antitumor activities of oncolytic adenovirus-mediated IL-24 expression in hepatocellular carcinoma
por: Wang, Cong-Jun, et al.
Publicado: (2012)

DRAM1 regulates apoptosis through increasing protein levels and lysosomal localization of BAX
por: Guan, J-J, et al.
Publicado: (2015)

Suppression effect of recombinant adenovirus vector containing hIL-24 on Hep-2 laryngeal carcinoma cells
por: CHEN, XUEMEI, et al.
Publicado: (2014)

Recombinant Oncolytic Adenovirus Combined with Cyclophosphamide Induces Synergy in the Treatment of Breast Cancer in vitro and in vivo
por: Wang, Jing, et al.
Publicado: (2022)

A novel oncolytic adenovirus based on simian adenovirus serotype 24
por: Cheng, Tao, et al.
Publicado: (2017)

Recombinant human arginase induced caspase-dependent apoptosis and autophagy in non-Hodgkin's lymphoma cells
por: Zeng, X, et al.
Publicado: (2013)

Transduction of dendritic cells with recombinant adenovirus encoding HCA661 activates autologous cytotoxic T lymphocytes to target hepatoma cells
por: Chan, R C-F, et al.
Publicado: (2004)

α2,6-Sialylation mediates hepatocellular carcinoma growth in vitro and in vivo by targeting the Wnt/β-catenin pathway
por: Zhao, Y, et al.
Publicado: (2017)

Enhancement of auranofin-induced lung cancer cell apoptosis by selenocystine, a natural inhibitor of TrxR1 in vitro and in vivo
por: Fan, C, et al.
Publicado: (2014)

Retraction Note: α2,6-Sialylation mediates hepatocellular carcinoma growth in vitro and in vivo by targeting the Wnt/β-catenin pathway
por: Zhao, Y., et al.
Publicado: (2020)

Recombinant adenovirus-mediated overexpression of 3β-hydroxysteroid-Δ24 reductase
por: Lu, Xiuli, et al.
Publicado: (2014)

Low nanomolar concentrations of Cucurbitacin-I induces G2/M phase arrest and apoptosis by perturbing redox homeostasis in gastric cancer cells in vitro and in vivo
por: Deng, C, et al.
Publicado: (2016)

Bax is essential for mitochondrion-mediated apoptosis but not for cell death caused by photodynamic therapy
por: Chiu, S-M, et al.
Publicado: (2003)

Robust autoactivation for apoptosis by BAK but not BAX highlights BAK as an important therapeutic target
por: Iyer, Sweta, et al.
Publicado: (2020)

Adenovirus Biology, Recombinant Adenovirus, and Adenovirus Usage in Gene Therapy
por: Watanabe, Maki, et al.
Publicado: (2021)

Recombinant Interferon-γ Lentivirus Co-Infection Inhibits Adenovirus Replication Ex Vivo
por: Zhang, Ling, et al.
Publicado: (2012)

Apoptosis, cell proliferation and expression of Bcl-2 and Bax in gastric carcinomas: immunohistochemical and clinicopathological study.
por: Koshida, Y., et al.
Publicado: (1997)

BAK/BAX-Mediated Apoptosis Is a Myc-Induced Roadblock to Reprogramming
por: Kim, Esther J.Y., et al.
Publicado: (2018)

Heat stress induced apoptosis is triggered by transcription-independent p53, Ca(2+) dyshomeostasis and the subsequent Bax mitochondrial translocation
por: Gu, Z. T., et al.
Publicado: (2015)

Bax/Bak activation in the absence of Bid, Bim, Puma, and p53
por: Zhang, J, et al.
Publicado: (2016)

Rescue of Recombinant Adenoviruses by CRISPR/Cas-Mediated in vivo Terminal Resolution
por: Riedl, André, et al.
Publicado: (2022)

Effect of ATP and Bax on the apoptosis of Eimeria tenella host cells
por: Xu, Zhiyong, et al.
Publicado: (2017)

Recombinant oncolytic adenovirus armed with CCL5, IL-12, and IFN-γ promotes CAR-T infiltration and proliferation in vivo to eradicate local and distal tumors
por: Fang, Lin, et al.
Publicado: (2023)

Bufarenogin induces intrinsic apoptosis via Bax and ANT cooperation
por: Han, Qinrui, et al.
Publicado: (2021)

PUMA and Bax-induced Autophagy Contributes to Apoptosis
por: Yee, Karen S., et al.
Publicado: (2009)

Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis
por: Zong, Wei-Xing, et al.
Publicado: (2003)

Oncolytic adenovirus-mediated mda-7/IL-24 expression suppresses osteosarcoma growth and enhances sensitivity to doxorubicin
por: Liu, Zongming, et al.
Publicado: (2021)

Osteogenesis induced in goat bone marrow progenitor cells by recombinant adenovirus coexpressing bone morphogenetic protein 2 and basic fibroblast growth factor
por: Xu, H.H., et al.
Publicado: (2013)

Lobaplatin induces apoptosis in T24 and 5637 bladder cancer cells by regulating Bcl-2 and Bax expression and inhibiting the PI3K/Akt signaling pathway
por: Yu, Qian, et al.
Publicado: (2023)

Cordycepin induces Bax-dependent apoptosis in colorectal cancer cells
por: Li, Shang-Ze, et al.
Publicado: (2019)

In Vivo and In Vitro Suppression of Hepatocellular Carcinoma by EF24, a Curcumin Analog
por: Liu, Haitao, et al.
Publicado: (2012)

VDAC2 enables BAX to mediate apoptosis and limit tumor development
por: Chin, Hui San, et al.
Publicado: (2018)

Complement activation by recombinant adenoviruses
por: Cichon, G, et al.
Publicado: (2002)

Apoptosis and Bax Expression are Increased by Coal Dust in the Polycyclic Aromatic Hydrocarbon-Exposed Lung
por: Ghanem, Mohamed M., et al.
Publicado: (2006)

Genistein sensitizes sarcoma cells in vitro and in vivo by enhancing apoptosis and by inhibiting DSB repair pathways
por: Liu, X.X., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_i82n09cm5tu92r6eu1iflhp3p5