Cargando…
The SSX Family of Cancer-Testis Antigens as Target Proteins for Tumor Therapy
Cancer-testis antigens (CTAs) represent an expanding class of tumor-associated proteins defined on the basis of their tissue-restricted expression to testis or ovary germline cells and frequent ectopic expression in tumor tissue. The expression of CTA in MHC class I-deficient germline cells makes th...
Autores principales: | Smith, Heath A., McNeel, Douglas G. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963798/ https://www.ncbi.nlm.nih.gov/pubmed/20981248 http://dx.doi.org/10.1155/2010/150591 |
Ejemplares similares
-
SSX expression and function in prostate cancer
por: Bloom, Jordan E, et al.
Publicado: (2013) -
Epitope optimization of a DNA vaccine targeting SSX-2 leads to PD-1 upregulation on antigen-specific CD8 T cells and PD-L1 upregulation on tumor cells
por: Rekoske, Brian, et al.
Publicado: (2013) -
SSX2 regulates focal adhesion but does not drive the epithelial to mesenchymal transition in prostate cancer
por: Bloom, Jordan E., et al.
Publicado: (2016) -
Oncogenic Functions of the Cancer-Testis Antigen SSX on the Proliferation, Survival, and Signaling Pathways of Cancer Cells
por: D’Arcy, Padraig, et al.
Publicado: (2014) -
Inducible expression of cancer-testis antigens in human prostate cancer
por: Heninger, Erika, et al.
Publicado: (2016)