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Direct Vasocontractile Activities of Bupivacaine Enantiomers on the Isolated Rat Thoracic Aorta

Background. In vitro studies with isolated arteries have shown direct vasoactivity of racemic bupivacaine. However, there is little information on the direct vasoactivities of bupivacaine enantiomers, S(−)- and R(+)-bupivacaine. Methods. We performed functional examinations using isolated intact tho...

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Detalles Bibliográficos
Autores principales: Mukozawa, Mai, Takakura, Ko, Mizogami, Maki
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964006/
https://www.ncbi.nlm.nih.gov/pubmed/20981258
http://dx.doi.org/10.1155/2010/820186