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Changing Trends of Breast Cancer Survival in Sultanate of Oman

Breast cancer is the leading cause of cancer-associated mortality in women, with elevated incidence in developing countries. This retrospective study included all 122 patients diagnosed with breast cancer from January 2003 to December 2008 in the Sultanate of Oman. Age at presentation was 47.41 year...

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Autores principales: Kumar, Shiyam, Burney, Ikram A., Al-Ajmi, Adel, Al-Moundhri, Mansour S.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964035/
https://www.ncbi.nlm.nih.gov/pubmed/20981261
http://dx.doi.org/10.1155/2011/316243
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author Kumar, Shiyam
Burney, Ikram A.
Al-Ajmi, Adel
Al-Moundhri, Mansour S.
author_facet Kumar, Shiyam
Burney, Ikram A.
Al-Ajmi, Adel
Al-Moundhri, Mansour S.
author_sort Kumar, Shiyam
collection PubMed
description Breast cancer is the leading cause of cancer-associated mortality in women, with elevated incidence in developing countries. This retrospective study included all 122 patients diagnosed with breast cancer from January 2003 to December 2008 in the Sultanate of Oman. Age at presentation was 47.41 years (SD±12.88), with one-third of patients younger than 40 years. The majority of patients presented with stage III (41.2%) and IV (18.2%) breast cancer. T size (P = .023), skin involvement (P = .003), and stage at presentation (P = .004) were significantly associated with overall survival. Skin involvement at presentation (P = .003), T size (P = .09), lymph node status (P = .013), and stage (P = .003) were strong predictors of relapse-free survival. Patients had a 5-year survival of 78%, compared to 64% of breast cancer patients diagnosed between 1996 and 2002 identified in our previously published study. Thus, despite Omani breast cancer patients continuing to present with advanced breast cancer, survival rates have significantly improved.
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spelling pubmed-29640352010-10-27 Changing Trends of Breast Cancer Survival in Sultanate of Oman Kumar, Shiyam Burney, Ikram A. Al-Ajmi, Adel Al-Moundhri, Mansour S. J Oncol Clinical Study Breast cancer is the leading cause of cancer-associated mortality in women, with elevated incidence in developing countries. This retrospective study included all 122 patients diagnosed with breast cancer from January 2003 to December 2008 in the Sultanate of Oman. Age at presentation was 47.41 years (SD±12.88), with one-third of patients younger than 40 years. The majority of patients presented with stage III (41.2%) and IV (18.2%) breast cancer. T size (P = .023), skin involvement (P = .003), and stage at presentation (P = .004) were significantly associated with overall survival. Skin involvement at presentation (P = .003), T size (P = .09), lymph node status (P = .013), and stage (P = .003) were strong predictors of relapse-free survival. Patients had a 5-year survival of 78%, compared to 64% of breast cancer patients diagnosed between 1996 and 2002 identified in our previously published study. Thus, despite Omani breast cancer patients continuing to present with advanced breast cancer, survival rates have significantly improved. Hindawi Publishing Corporation 2011 2010-10-25 /pmc/articles/PMC2964035/ /pubmed/20981261 http://dx.doi.org/10.1155/2011/316243 Text en Copyright © 2011 Shiyam Kumar et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Kumar, Shiyam
Burney, Ikram A.
Al-Ajmi, Adel
Al-Moundhri, Mansour S.
Changing Trends of Breast Cancer Survival in Sultanate of Oman
title Changing Trends of Breast Cancer Survival in Sultanate of Oman
title_full Changing Trends of Breast Cancer Survival in Sultanate of Oman
title_fullStr Changing Trends of Breast Cancer Survival in Sultanate of Oman
title_full_unstemmed Changing Trends of Breast Cancer Survival in Sultanate of Oman
title_short Changing Trends of Breast Cancer Survival in Sultanate of Oman
title_sort changing trends of breast cancer survival in sultanate of oman
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964035/
https://www.ncbi.nlm.nih.gov/pubmed/20981261
http://dx.doi.org/10.1155/2011/316243
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