HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology

We present HepatoNet1, the first reconstruction of a comprehensive metabolic network of the human hepatocyte that is shown to accomplish a large canon of known metabolic liver functions. The network comprises 777 metabolites in six intracellular and two extracellular compartments and 2539 reactions,...

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Detalles Bibliográficos
Autores principales: Gille, Christoph, Bölling, Christian, Hoppe, Andreas, Bulik, Sascha, Hoffmann, Sabrina, Hübner, Katrin, Karlstädt, Anja, Ganeshan, Ramanan, König, Matthias, Rother, Kristian, Weidlich, Michael, Behre, Jörn, Holzhütter, Herrmann-Georg
Formato: Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964118/
https://www.ncbi.nlm.nih.gov/pubmed/20823849
http://dx.doi.org/10.1038/msb.2010.62

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964118/
https://www.ncbi.nlm.nih.gov/pubmed/20823849
http://dx.doi.org/10.1038/msb.2010.62

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