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An interdomain sector mediating allostery in Hsp70 molecular chaperones
Allosteric coupling between protein domains is fundamental to many cellular processes. For example, Hsp70 molecular chaperones use ATP binding by their actin-like N-terminal ATPase domain to control substrate interactions in their C-terminal substrate-binding domain, a reaction that is critical for...
Autores principales: | Smock, Robert G, Rivoire, Olivier, Russ, William P, Swain, Joanna F, Leibler, Stanislas, Ranganathan, Rama, Gierasch, Lila M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964120/ https://www.ncbi.nlm.nih.gov/pubmed/20865007 http://dx.doi.org/10.1038/msb.2010.65 |
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