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Human α3β4 Neuronal Nicotinic Receptors Show Different Stoichiometry if They Are Expressed in Xenopus Oocytes or Mammalian HEK293 Cells
BACKGROUND: The neuronal nicotinic receptors that mediate excitatory transmission in autonomic ganglia are thought to be formed mainly by the α3 and β4 subunits. Expressing this composition in oocytes fails to reproduce the properties of ganglionic receptors, which may also incorporate the α5 and/or...
Autores principales: | Krashia, Paraskevi, Moroni, Mirko, Broadbent, Steven, Hofmann, Giovanna, Kracun, Sebastian, Beato, Marco, Groot-Kormelink, Paul J., Sivilotti, Lucia G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964301/ https://www.ncbi.nlm.nih.gov/pubmed/21049012 http://dx.doi.org/10.1371/journal.pone.0013611 |
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