Cargando…
Glial Innate Immunity Generated by Non-Aggregated Alpha-Synuclein in Mouse: Differences between Wild-type and Parkinson's Disease-Linked Mutants
BACKGROUND: Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized pathologically by the presence in the brain of intracellular protein inclusions highly enriched in aggregated alpha-synuclein (α-Syn). Although it has been established that progression of the disease...
Autores principales: | Roodveldt, Cintia, Labrador-Garrido, Adahir, Gonzalez-Rey, Elena, Fernandez-Montesinos, Rafael, Caro, Marta, Lachaud, Christian C., Waudby, Christopher A., Delgado, Mario, Dobson, Christopher M., Pozo, David |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964342/ https://www.ncbi.nlm.nih.gov/pubmed/21048992 http://dx.doi.org/10.1371/journal.pone.0013481 |
Ejemplares similares
-
Preconditioning of Microglia by α-Synuclein Strongly Affects the Response Induced by Toll-like Receptor (TLR) Stimulation
por: Roodveldt, Cintia, et al.
Publicado: (2013) -
Chaperoned amyloid proteins for immune manipulation: α-Synuclein/Hsp70 shifts immunity toward a modulatory phenotype
por: Labrador-Garrido, Adahir, et al.
Publicado: (2014) -
Immunological features of α-synuclein in Parkinson's disease
por: Roodveldt, Cintia, et al.
Publicado: (2008) -
Live cell in situ lysosomal GCase activity correlates to alpha-synuclein levels in human differentiated neurons with LRRK2 and GBA1 mutations
por: Labrador-Garrido, Adahir, et al.
Publicado: (2023) -
Conformational templating of α-synuclein aggregates in neuronal-glial cultures
por: Sacino, Amanda N, et al.
Publicado: (2013)