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Inhibition of Osteoclastogenesis by Mechanically Loaded Osteocytes: Involvement of MEPE

In regions of high bone loading, the mechanoresponsive osteocytes inhibit osteoclastic bone resorption by producing signaling molecules. One possible candidate is matrix extracellular phosphoglycoprotein (MEPE) because acidic serine- and aspartate-rich MEPE-associated motif peptides upregulate osteo...

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Detalles Bibliográficos
Autores principales:	Kulkarni, Rishikesh N., Bakker, Astrid D., Everts, Vincent, Klein-Nulend, Jenneke
Formato:	Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964475/ https://www.ncbi.nlm.nih.gov/pubmed/20725825 http://dx.doi.org/10.1007/s00223-010-9407-7

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