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Biocleavable Polycationic Micelles as Highly Efficient Gene Delivery Vectors

An amphiphilic disulfide-containing polyamidoamine was synthesized by Michael-type polyaddition reaction of piperazine to equimolar N, N′-bis(acryloyl)cystamine with 90% yield. The polycationic micelles (198 nm, 32.5 mV), prepared from the amphiphilic polyamidoamine by dialysis method, can condense...

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Detalles Bibliográficos
Autores principales: Zhang, Min, Xue, Ya-Nan, Liu, Min, Zhuo, Ren-Xi, Huang, Shi-Wen
Formato: Texto
Lenguaje:English
Publicado: Springer 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964480/
https://www.ncbi.nlm.nih.gov/pubmed/21124632
http://dx.doi.org/10.1007/s11671-010-9716-9