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CTD small phosphatase like 2 (CTDSPL2) can increase ε- and γ-globin gene expression in K562 cells and CD34+ cells derived from umbilical cord blood

BACKGROUND: A potential strategy for treatment of sickle cell disease (SCD) and β-thalassemia in adults is reactivation of the ε- and γ-globin genes in the adult. We aimed to identify trans-activators of ε- and γ-globin expression and provide new candidate targets for effective treatment of sickle c...

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Detalles Bibliográficos
Autores principales:	Ma, Yan-Ni, Zhang, Xin, Yu, Hai-Chuan, Zhang, Jun-Wu
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964535/ https://www.ncbi.nlm.nih.gov/pubmed/20932329 http://dx.doi.org/10.1186/1471-2121-11-75

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