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Coordinate suppression of B cell lymphoma by PTEN and SHIP phosphatases
The inositol phosphatases phosphatase and tensin homologue (PTEN) and Src homology 2 domain–containing inositol phosphatase (SHIP) negatively regulate phosphatidylinositol-3-kinase (PI3K)–mediated growth, survival, and proliferation of hematopoietic cells. Although deletion of PTEN in mouse T cells...
Autores principales: | Miletic, Ana V., Anzelon-Mills, Amy N., Mills, David M., Omori, Sidne A., Pedersen, Irene M., Shin, Dong-Mi, Ravetch, Jeffrey V., Bolland, Silvia, Morse, Herbert C., Rickert, Robert C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964567/ https://www.ncbi.nlm.nih.gov/pubmed/20956547 http://dx.doi.org/10.1084/jem.20091962 |
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