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HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment
Myeloid-derived suppressor cells (MDSCs) are a major component of the immune-suppressive network described in cancer and many other pathological conditions. We demonstrate that although MDSCs from peripheral lymphoid organs and the tumor site share similar phenotype and morphology, these cells displ...
Autores principales: | Corzo, Cesar A., Condamine, Thomas, Lu, Lily, Cotter, Matthew J., Youn, Je-In, Cheng, Pingyan, Cho, Hyun-Il, Celis, Esteban, Quiceno, David G., Padhya, Tapan, McCaffrey, Thomas V., McCaffrey, Judith C., Gabrilovich, Dmitry I. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964584/ https://www.ncbi.nlm.nih.gov/pubmed/20876310 http://dx.doi.org/10.1084/jem.20100587 |
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