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HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

Myeloid-derived suppressor cells (MDSCs) are a major component of the immune-suppressive network described in cancer and many other pathological conditions. We demonstrate that although MDSCs from peripheral lymphoid organs and the tumor site share similar phenotype and morphology, these cells displ...

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Detalles Bibliográficos
Autores principales: Corzo, Cesar A., Condamine, Thomas, Lu, Lily, Cotter, Matthew J., Youn, Je-In, Cheng, Pingyan, Cho, Hyun-Il, Celis, Esteban, Quiceno, David G., Padhya, Tapan, McCaffrey, Thomas V., McCaffrey, Judith C., Gabrilovich, Dmitry I.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964584/
https://www.ncbi.nlm.nih.gov/pubmed/20876310
http://dx.doi.org/10.1084/jem.20100587

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