Cargando…
Shortcomings of short hairpin RNA-based transgenic RNA interference in mouse oocytes
BACKGROUND: RNA interference (RNAi) is a powerful approach to study a gene function. Transgenic RNAi is an adaptation of this approach where suppression of a specific gene is achieved by expression of an RNA hairpin from a transgene. In somatic cells, where a long double-stranded RNA (dsRNA) longer...
| Autores principales: | , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964603/ https://www.ncbi.nlm.nih.gov/pubmed/20939886 http://dx.doi.org/10.1186/1477-5751-9-8 |