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Mutations that permit residual CFTR function delay acquisition of multiple respiratory pathogens in CF patients

BACKGROUND: Lung infection by various organisms is a characteristic feature of cystic fibrosis (CF). CFTR genotype effects acquisition of Pseudomonas aeruginosa (Pa), however the effect on acquisition of other infectious organisms that frequently precede Pa is relatively unknown. Understanding the r...

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Detalles Bibliográficos
Autores principales: Green, Deanna M, McDougal, Kathryn E, Blackman, Scott M, Sosnay, Patrick R, Henderson, Lindsay B, Naughton, Kathleen M, Collaco, J Michael, Cutting, Garry R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964615/
https://www.ncbi.nlm.nih.gov/pubmed/20932301
http://dx.doi.org/10.1186/1465-9921-11-140

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