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Lipoprotein biosynthesis as a target for anti-Wolbachia treatment of filarial nematodes

BACKGROUND: Lymphatic filariasis and onchocerciasis are debilitating diseases caused by filarial nematodes. Disease pathogenesis is induced by inflammatory responses following the death of the parasite. Wolbachia endosymbionts of filariae are potent inducers of innate and adaptive inflammation and b...

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Detalles Bibliográficos
Autores principales: Johnston, Kelly L, Wu, Bo, Guimarães, Ana, Ford, Louise, Slatko, Barton E, Taylor, Mark J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964653/
https://www.ncbi.nlm.nih.gov/pubmed/20946650
http://dx.doi.org/10.1186/1756-3305-3-99

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