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Lipoprotein biosynthesis as a target for anti-Wolbachia treatment of filarial nematodes
BACKGROUND: Lymphatic filariasis and onchocerciasis are debilitating diseases caused by filarial nematodes. Disease pathogenesis is induced by inflammatory responses following the death of the parasite. Wolbachia endosymbionts of filariae are potent inducers of innate and adaptive inflammation and b...
Autores principales: | Johnston, Kelly L, Wu, Bo, Guimarães, Ana, Ford, Louise, Slatko, Barton E, Taylor, Mark J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964653/ https://www.ncbi.nlm.nih.gov/pubmed/20946650 http://dx.doi.org/10.1186/1756-3305-3-99 |
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