Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines

BACKGROUND: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic reactions suggests a potential way to discover drug targets. RESULTS: In this paper, we present a computational method to pred...

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Detalles Bibliográficos
Autores principales: Li, Limin, Zhou, Xiaobo, Ching, Wai-Ki, Wang, Ping
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964682/
https://www.ncbi.nlm.nih.gov/pubmed/20932284
http://dx.doi.org/10.1186/1471-2105-11-501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964682/
https://www.ncbi.nlm.nih.gov/pubmed/20932284
http://dx.doi.org/10.1186/1471-2105-11-501

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