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Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
BACKGROUND: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic reactions suggests a potential way to discover drug targets. RESULTS: In this paper, we present a computational method to pred...
Autores principales: | Li, Limin, Zhou, Xiaobo, Ching, Wai-Ki, Wang, Ping |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964682/ https://www.ncbi.nlm.nih.gov/pubmed/20932284 http://dx.doi.org/10.1186/1471-2105-11-501 |
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