Formulation Development, Evaluation and Comparative Study of Effects of Super Disintegrants in Cefixime Oral Disintegrating Tablets

The present work was aimed at formulation development, evaluation and comparative study of the effects of superdisintegrants in Cefixime 50 mg oral disintegrating tablets. The superdisintegrants used for the present study were sodium starch glycolate and crosscarmellose sodium. The formulated tablet...

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Detalles Bibliográficos
Autores principales: Remya, KS, Beena, P, Bijesh, PV, Sheeba, A
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Pharmaceutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964761/
https://www.ncbi.nlm.nih.gov/pubmed/21042477
http://dx.doi.org/10.4103/0975-1483.66794
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author Remya, KS
Beena, P
Bijesh, PV
Sheeba, A
author_facet Remya, KS
Beena, P
Bijesh, PV
Sheeba, A
author_sort Remya, KS
collection PubMed
description The present work was aimed at formulation development, evaluation and comparative study of the effects of superdisintegrants in Cefixime 50 mg oral disintegrating tablets. The superdisintegrants used for the present study were sodium starch glycolate and crosscarmellose sodium. The formulated tablets were evaluated for various tableting properties, like hardness, thickness, friability, weight variation, disintegration time and dissolution rate. Comparative evaluation of the above-mentioned parameters established the superiority of the tablets formulated with crosscarmellose sodium to those formulated with sodium starch glycolate.
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spelling pubmed-29647612010-11-01 Formulation Development, Evaluation and Comparative Study of Effects of Super Disintegrants in Cefixime Oral Disintegrating Tablets Remya, KS Beena, P Bijesh, PV Sheeba, A J Young Pharm Pharmaceutics The present work was aimed at formulation development, evaluation and comparative study of the effects of superdisintegrants in Cefixime 50 mg oral disintegrating tablets. The superdisintegrants used for the present study were sodium starch glycolate and crosscarmellose sodium. The formulated tablets were evaluated for various tableting properties, like hardness, thickness, friability, weight variation, disintegration time and dissolution rate. Comparative evaluation of the above-mentioned parameters established the superiority of the tablets formulated with crosscarmellose sodium to those formulated with sodium starch glycolate. Medknow Publications 2010 /pmc/articles/PMC2964761/ /pubmed/21042477 http://dx.doi.org/10.4103/0975-1483.66794 Text en © Journal of Young Pharmacists http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Pharmaceutics
Remya, KS
Beena, P
Bijesh, PV
Sheeba, A
Formulation Development, Evaluation and Comparative Study of Effects of Super Disintegrants in Cefixime Oral Disintegrating Tablets
title Formulation Development, Evaluation and Comparative Study of Effects of Super Disintegrants in Cefixime Oral Disintegrating Tablets
title_full Formulation Development, Evaluation and Comparative Study of Effects of Super Disintegrants in Cefixime Oral Disintegrating Tablets
title_fullStr Formulation Development, Evaluation and Comparative Study of Effects of Super Disintegrants in Cefixime Oral Disintegrating Tablets
title_full_unstemmed Formulation Development, Evaluation and Comparative Study of Effects of Super Disintegrants in Cefixime Oral Disintegrating Tablets
title_short Formulation Development, Evaluation and Comparative Study of Effects of Super Disintegrants in Cefixime Oral Disintegrating Tablets
title_sort formulation development, evaluation and comparative study of effects of super disintegrants in cefixime oral disintegrating tablets
topic Pharmaceutics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964761/
https://www.ncbi.nlm.nih.gov/pubmed/21042477
http://dx.doi.org/10.4103/0975-1483.66794
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AT bijeshpv formulationdevelopmentevaluationandcomparativestudyofeffectsofsuperdisintegrantsincefiximeoraldisintegratingtablets
AT sheebaa formulationdevelopmentevaluationandcomparativestudyofeffectsofsuperdisintegrantsincefiximeoraldisintegratingtablets

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