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Pediatric stroke in an African country

BACKGROUND: The pattern of pediatric stroke displays ethnic and geographical variations. There are few reports from black Sub-Saharan Africa, although relevant data are important in prevention, clinical diagnosis, treatment and prognostication. AIM: To describe subtypes, risk factors, localization,...

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Autores principales: Ogeng’o, Julius Alexander, Olabu, Beda O., Mburu, Anne N., Sinkeet, Simeon R.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964794/
https://www.ncbi.nlm.nih.gov/pubmed/21042501
http://dx.doi.org/10.4103/1817-1745.66676
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author Ogeng’o, Julius Alexander
Olabu, Beda O.
Mburu, Anne N.
Sinkeet, Simeon R.
author_facet Ogeng’o, Julius Alexander
Olabu, Beda O.
Mburu, Anne N.
Sinkeet, Simeon R.
author_sort Ogeng’o, Julius Alexander
collection PubMed
description BACKGROUND: The pattern of pediatric stroke displays ethnic and geographical variations. There are few reports from black Sub-Saharan Africa, although relevant data are important in prevention, clinical diagnosis, treatment and prognostication. AIM: To describe subtypes, risk factors, localization, age and gender distribution of pediatric stroke in the black Kenyan population. STUDY DESIGN AND SETTING: Retrospective cross-sectional study in a single regional referral and teaching hospital. STATISTICAL ANALYSIS: Data were analyzed by SPSS version 13.0 for Windows and presented in tables and bar and pie charts. MATERIALS AND METHODS: The study was performed at the Kenyatta National Hospital, a level-6 regional referral health facility with an annual pediatric in-patient turnover of about 40,000 patients. Files of patients aged 1 month to 18 years over a period of 5 years were analyzed for stroke subtypes, localization, risk factors, age and sex distribution. Only those files with complete information were included. RESULTS: Thirty-two of the 712 stroke patients (4.5%) were pediatric. The male:female ratio was 1.7:1. Ischemic stroke comprised 56.3% (n = 18). Mean age was 7.7 years (range, 1.5–18 years). The most common sites were cortical (51%), lacunar (41%) and brain stem (8%). The most common risk factors were connective tissue disorders (28.1%), heart disease (25%), human immunodeficiency virus (9.4%) and infection (9.4%). CONCLUSION: Pediatric stroke is not uncommon in the Kenyan population. The risk factor profile comprising connective tissue disorders and infection differs from that reported in other populations, inviting large community-based studies.
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spelling pubmed-29647942010-11-01 Pediatric stroke in an African country Ogeng’o, Julius Alexander Olabu, Beda O. Mburu, Anne N. Sinkeet, Simeon R. J Pediatr Neurosci Original Article BACKGROUND: The pattern of pediatric stroke displays ethnic and geographical variations. There are few reports from black Sub-Saharan Africa, although relevant data are important in prevention, clinical diagnosis, treatment and prognostication. AIM: To describe subtypes, risk factors, localization, age and gender distribution of pediatric stroke in the black Kenyan population. STUDY DESIGN AND SETTING: Retrospective cross-sectional study in a single regional referral and teaching hospital. STATISTICAL ANALYSIS: Data were analyzed by SPSS version 13.0 for Windows and presented in tables and bar and pie charts. MATERIALS AND METHODS: The study was performed at the Kenyatta National Hospital, a level-6 regional referral health facility with an annual pediatric in-patient turnover of about 40,000 patients. Files of patients aged 1 month to 18 years over a period of 5 years were analyzed for stroke subtypes, localization, risk factors, age and sex distribution. Only those files with complete information were included. RESULTS: Thirty-two of the 712 stroke patients (4.5%) were pediatric. The male:female ratio was 1.7:1. Ischemic stroke comprised 56.3% (n = 18). Mean age was 7.7 years (range, 1.5–18 years). The most common sites were cortical (51%), lacunar (41%) and brain stem (8%). The most common risk factors were connective tissue disorders (28.1%), heart disease (25%), human immunodeficiency virus (9.4%) and infection (9.4%). CONCLUSION: Pediatric stroke is not uncommon in the Kenyan population. The risk factor profile comprising connective tissue disorders and infection differs from that reported in other populations, inviting large community-based studies. Medknow Publications 2010 /pmc/articles/PMC2964794/ /pubmed/21042501 http://dx.doi.org/10.4103/1817-1745.66676 Text en © Journal of Pediatric Neurosciences http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Ogeng’o, Julius Alexander
Olabu, Beda O.
Mburu, Anne N.
Sinkeet, Simeon R.
Pediatric stroke in an African country
title Pediatric stroke in an African country
title_full Pediatric stroke in an African country
title_fullStr Pediatric stroke in an African country
title_full_unstemmed Pediatric stroke in an African country
title_short Pediatric stroke in an African country
title_sort pediatric stroke in an african country
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964794/
https://www.ncbi.nlm.nih.gov/pubmed/21042501
http://dx.doi.org/10.4103/1817-1745.66676
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