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Sarcomatoid chromophobe renal cell carcinoma: Cytohistopathological correlation of a case
Sarcomatoid renal cell carcinomas of the kidney are rare neoplasms constituting about 1-5% of all renal malignant neoplasms. These are aggressive tumors and are commonly associated with conventional (clear cell) renal cell carcinomas, but cases associated with chromophobe renal cell carcinomas are s...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Medknow Publications
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964855/ https://www.ncbi.nlm.nih.gov/pubmed/21042532 http://dx.doi.org/10.4103/0970-9371.66690 |
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author | Chakrabarti, Indranil Giri, Amita Majumdar, Kaushik Anuradha, DE |
author_facet | Chakrabarti, Indranil Giri, Amita Majumdar, Kaushik Anuradha, DE |
author_sort | Chakrabarti, Indranil |
collection | PubMed |
description | Sarcomatoid renal cell carcinomas of the kidney are rare neoplasms constituting about 1-5% of all renal malignant neoplasms. These are aggressive tumors and are commonly associated with conventional (clear cell) renal cell carcinomas, but cases associated with chromophobe renal cell carcinomas are sparse. Cytological features of such lesions have rarely been reported. Here, we report a unique case of a 48-year-old male patient who presented with right flank lump and pain. A fine needle aspiration was performed from the lesion under ultrasound guidance and a cytological diagnosis of pleomorphic sarcoma was made. A right-sided radical nephrectomy was carried out and subsequent histopathology revealed a sarcomatoid renal cell carcinoma with wide areas of necrosis coexisting with chromophobe renal cell carcinoma with calcification. Differentiation of pleomorphic sarcoma from a sarcomatoid renal cell carcinoma is, thus, challenging from cytopathology smears and the differential diagnoses should always be borne in mind while giving a cytopathological opinion. |
format | Text |
id | pubmed-2964855 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Medknow Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-29648552010-11-01 Sarcomatoid chromophobe renal cell carcinoma: Cytohistopathological correlation of a case Chakrabarti, Indranil Giri, Amita Majumdar, Kaushik Anuradha, DE J Cytol Case Report Sarcomatoid renal cell carcinomas of the kidney are rare neoplasms constituting about 1-5% of all renal malignant neoplasms. These are aggressive tumors and are commonly associated with conventional (clear cell) renal cell carcinomas, but cases associated with chromophobe renal cell carcinomas are sparse. Cytological features of such lesions have rarely been reported. Here, we report a unique case of a 48-year-old male patient who presented with right flank lump and pain. A fine needle aspiration was performed from the lesion under ultrasound guidance and a cytological diagnosis of pleomorphic sarcoma was made. A right-sided radical nephrectomy was carried out and subsequent histopathology revealed a sarcomatoid renal cell carcinoma with wide areas of necrosis coexisting with chromophobe renal cell carcinoma with calcification. Differentiation of pleomorphic sarcoma from a sarcomatoid renal cell carcinoma is, thus, challenging from cytopathology smears and the differential diagnoses should always be borne in mind while giving a cytopathological opinion. Medknow Publications 2010-01 /pmc/articles/PMC2964855/ /pubmed/21042532 http://dx.doi.org/10.4103/0970-9371.66690 Text en © Journal of Cytology http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Chakrabarti, Indranil Giri, Amita Majumdar, Kaushik Anuradha, DE Sarcomatoid chromophobe renal cell carcinoma: Cytohistopathological correlation of a case |
title | Sarcomatoid chromophobe renal cell carcinoma: Cytohistopathological correlation of a case |
title_full | Sarcomatoid chromophobe renal cell carcinoma: Cytohistopathological correlation of a case |
title_fullStr | Sarcomatoid chromophobe renal cell carcinoma: Cytohistopathological correlation of a case |
title_full_unstemmed | Sarcomatoid chromophobe renal cell carcinoma: Cytohistopathological correlation of a case |
title_short | Sarcomatoid chromophobe renal cell carcinoma: Cytohistopathological correlation of a case |
title_sort | sarcomatoid chromophobe renal cell carcinoma: cytohistopathological correlation of a case |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964855/ https://www.ncbi.nlm.nih.gov/pubmed/21042532 http://dx.doi.org/10.4103/0970-9371.66690 |
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