Sli15(INCENP) Dephosphorylation Prevents Mitotic Checkpoint Reengagement Due to Loss of Tension at Anaphase Onset

The mitotic checkpoint, also known as the spindle assembly checkpoint, delays anaphase onset until all chromosomes have reached bipolar tension on the mitotic spindle [1–3]. Once this is achieved, the protease separase is activated to cleave the chromosomal cohesin complex, thereby triggering anapha...

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Detalles Bibliográficos
Autores principales: Mirchenko, Lesia, Uhlmann, Frank
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964898/
https://www.ncbi.nlm.nih.gov/pubmed/20619650
http://dx.doi.org/10.1016/j.cub.2010.06.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964898/
https://www.ncbi.nlm.nih.gov/pubmed/20619650
http://dx.doi.org/10.1016/j.cub.2010.06.023

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