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Molecular basis of FIR-mediated c-myc transcriptional control

The Far UpStream Element (FUSE) regulatory system promotes a peak in the concentration of c-Myc during cell cycle. First, the FBP transcriptional activator binds to the FUSE DNA element upstream of the c-myc promoter. Then, FBP recruits its specific repressor (FIR) which acts as an on/off transcript...

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Detalles Bibliográficos
Autores principales:	Cukier, Cyprian D., Hollingworth, David, Martin, Stephen R., Kelly, Geoff, Díaz-Moreno, Irene, Ramos, Andres
Formato:	Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964917/ https://www.ncbi.nlm.nih.gov/pubmed/20711187 http://dx.doi.org/10.1038/nsmb.1883

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