ATM Modulates the Loading of Recombination Proteins onto a Chromosomal Translocation Breakpoint Hotspot

Chromosome translocations induced by DNA damaging agents, such as ionizing radiation and certain chemotherapies, alter genetic information resulting in malignant transformation. Abrogation or loss of the ataxia-telangiectasia mutated (ATM) protein, a DNA damage signaling regulator, increases the inc...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Jiying, Oma, Yukako, Harata, Masahiko, Kono, Kazuteru, Shima, Hiroki, Kinomura, Aiko, Ikura, Tsuyoshi, Suzuki, Hidekazu, Mizutani, Shuki, Kanaar, Roland, Tashiro, Satoshi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965082/
https://www.ncbi.nlm.nih.gov/pubmed/21048951
http://dx.doi.org/10.1371/journal.pone.0013554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965082/
https://www.ncbi.nlm.nih.gov/pubmed/21048951
http://dx.doi.org/10.1371/journal.pone.0013554

Ejemplares similares