Dexamethasone Treatment Induces the Reprogramming of Pancreatic Acinar Cells to Hepatocytes and Ductal Cells

BACKGROUND: The pancreatic exocrine cell line AR42J-B13 can be reprogrammed to hepatocytes following treatment with dexamethasone. The question arises whether dexamethasone also has the capacity to induce ductal cells as well as hepatocytes. METHODOLOGY/PRINCIPAL FINDINGS: AR42J-B13 cells were treat...

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Detalles Bibliográficos
Autores principales: Al-Adsani, Amani, Burke, Zoë D., Eberhard, Daniel, Lawrence, Katherine L., Shen, Chia-Ning, Rustgi, Anil K., Sakaue, Hiroshi, Farrant, J. Mark, Tosh, David
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965100/
https://www.ncbi.nlm.nih.gov/pubmed/21048969
http://dx.doi.org/10.1371/journal.pone.0013650

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