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Regulation of miRNA Transcription in Macrophages in Response to Candida albicans

Macrophages detect pathogens via pattern recognition receptors (PRRs), which trigger several intracellular signaling cascades including the MAPK and NFκB pathways. These in turn mediate the up-regulation of pro-inflammatory cytokines that are essential to combat the pathogen. However as the over-pro...

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Detalles Bibliográficos
Autores principales: Monk, Claire E., Hutvagner, György, Arthur, J. Simon C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965114/
https://www.ncbi.nlm.nih.gov/pubmed/21060679
http://dx.doi.org/10.1371/journal.pone.0013669