Transcriptional regulation of Elf-1: locus-wide analysis reveals four distinct promoters, a tissue-specific enhancer, control by PU.1 and the importance of Elf-1 downregulation for erythroid maturation

Ets transcription factors play important roles during the development and maintenance of the haematopoietic system. One such factor, Elf-1 (E74-like factor 1) controls the expression of multiple essential haematopoietic regulators including Scl/Tal1, Lmo2 and PU.1. However, to integrate Elf-1 into t...

Descripción completa

Detalles Bibliográficos
Autores principales: Calero-Nieto, Fernando J., Wood, Andrew D., Wilson, Nicola K., Kinston, Sarah, Landry, Josette-Renée, Göttgens, Berthold
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965225/
https://www.ncbi.nlm.nih.gov/pubmed/20525788
http://dx.doi.org/10.1093/nar/gkq490

Ejemplares similares

Ejemplares similares