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Effect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNA

Telomerase extends the 3′-ends of linear chromosomes by adding conserved telomeric DNA repeats and is essential for cell proliferation and genomic stability. Telomerases from all organisms contain a telomerase reverse transcriptase and a telomerase RNA (TER), which together provide the minimal funct...

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Detalles Bibliográficos
Autores principales:	Kim, Nak-Kyoon, Theimer, Carla A., Mitchell, James R., Collins, Kathleen, Feigon, Juli
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965242/ https://www.ncbi.nlm.nih.gov/pubmed/20554853 http://dx.doi.org/10.1093/nar/gkq525

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