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Maintenance of respiratory chain function in mouse hearts with severely impaired mtDNA transcription
The basal mitochondrial transcription machinery is essential for biogenesis of the respiratory chain and consists of mitochondrial RNA polymerase, mitochondrial transcription factor A (TFAM) and mitochondrial transcription factor B2. This triad of proteins is sufficient and necessary for mtDNA trans...
Autores principales: | Freyer, Christoph, Park, Chan Bae, Ekstrand, Mats I., Shi, Yonghong, Khvorostova, Julia, Wibom, Rolf, Falkenberg, Maria, Gustafsson, Claes M., Larsson, Nils-Göran |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965244/ https://www.ncbi.nlm.nih.gov/pubmed/20566479 http://dx.doi.org/10.1093/nar/gkq527 |
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