Cargando…
A switch-on mechanism to activate maize ribosome-inactivating protein for targeting HIV-infected cells
Maize ribosome-inactivating protein (RIP) is a plant toxin that inactivates eukaryotic ribosomes by depurinating a specific adenine residue at the α-sarcin/ricin loop of 28S rRNA. Maize RIP is first produced as a proenzyme with a 25-amino acid internal inactivation region on the protein surface. Dur...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965250/ https://www.ncbi.nlm.nih.gov/pubmed/20558598 http://dx.doi.org/10.1093/nar/gkq551 |