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Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA
The recent discovery of genomic 5-hydroxymethylcytosine (hmC) and mutations affecting the respective Tet hydroxylases in leukemia raises fundamental questions about this epigenetic modification. We present a sensitive method for fast quantification of genomic hmC based on specific transfer of radiol...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965258/ https://www.ncbi.nlm.nih.gov/pubmed/20685817 http://dx.doi.org/10.1093/nar/gkq684 |