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A method for genome-wide analysis of DNA helical tension by means of psoralen–DNA photobinding
The helical tension of chromosomal DNA is one of the epigenetic landmarks most difficult to examine experimentally. The occurrence of DNA crosslinks mediated by psoralen photobinding (PB) stands as the only suitable probe for assessing this problem. PB is affected by chromatin structure when is done...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965259/ https://www.ncbi.nlm.nih.gov/pubmed/20685815 http://dx.doi.org/10.1093/nar/gkq687 |