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A method for genome-wide analysis of DNA helical tension by means of psoralen–DNA photobinding

The helical tension of chromosomal DNA is one of the epigenetic landmarks most difficult to examine experimentally. The occurrence of DNA crosslinks mediated by psoralen photobinding (PB) stands as the only suitable probe for assessing this problem. PB is affected by chromatin structure when is done...

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Detalles Bibliográficos
Autores principales: Bermúdez, Ignacio, García-Martínez, José, Pérez-Ortín, José E., Roca, Joaquim
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965259/
https://www.ncbi.nlm.nih.gov/pubmed/20685815
http://dx.doi.org/10.1093/nar/gkq687

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