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Nutritional Rickets among Children in a Sun Rich Country

Objective. This study describes the magnitude and characteristics of nutritional rickets and associated risk factors among children in Qatar. Subjects. A consecutive sample of 730 healthy subjects who visited the primay health care clinics were approached and 540 (73.9%) subjects gave consent. Mehod...

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Autores principales: Bener, Abdulbari, Hoffmann, Georg F.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965426/
https://www.ncbi.nlm.nih.gov/pubmed/21048925
http://dx.doi.org/10.1155/2010/410502
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author Bener, Abdulbari
Hoffmann, Georg F.
author_facet Bener, Abdulbari
Hoffmann, Georg F.
author_sort Bener, Abdulbari
collection PubMed
description Objective. This study describes the magnitude and characteristics of nutritional rickets and associated risk factors among children in Qatar. Subjects. A consecutive sample of 730 healthy subjects who visited the primay health care clinics were approached and 540 (73.9%) subjects gave consent. Mehods. Nutritional rickets diagnosis was based on clinical radiologic and biochemical parameters and normalization of alkaline phosphatase level after 6 weeks course of daily vitamin D therapy. Results. The study revealed that 23.9% of the studied children had nutritional rickets. The mean ± SD age of those with rickets (3.76 years ± 1.51) was slightly higher than those without rickets (3.57 years ± 1.45). Family history of vitamin D deficiency (44.2%; P = .001) and diabetes mellitus (53.5%; P = .002) were significantly higher in rachitic children than in nonrachitic children. The children with rickets spent a significantly shorter average duration (26.86 minutes ± 19.94) under the sun than those without rickets (30.59 minutes ± 15.72; P < .001). A significantly larger proportion of rachitic children was afflicted with vitamin D deficiency (75.2% versus 62.2%; P < .001), secondary hypothyroidism (100% versus 7.5%; P = .009) and muscular weakness (56.6% versus 26.3%; P < .001). Conclusion. The most important risk factors were low vitamin D and calcium intakes, lack of exposure to sunlight, prolonged breast feeding without supplementation of vitamin D.
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spelling pubmed-29654262010-11-03 Nutritional Rickets among Children in a Sun Rich Country Bener, Abdulbari Hoffmann, Georg F. Int J Pediatr Endocrinol Clinical Study Objective. This study describes the magnitude and characteristics of nutritional rickets and associated risk factors among children in Qatar. Subjects. A consecutive sample of 730 healthy subjects who visited the primay health care clinics were approached and 540 (73.9%) subjects gave consent. Mehods. Nutritional rickets diagnosis was based on clinical radiologic and biochemical parameters and normalization of alkaline phosphatase level after 6 weeks course of daily vitamin D therapy. Results. The study revealed that 23.9% of the studied children had nutritional rickets. The mean ± SD age of those with rickets (3.76 years ± 1.51) was slightly higher than those without rickets (3.57 years ± 1.45). Family history of vitamin D deficiency (44.2%; P = .001) and diabetes mellitus (53.5%; P = .002) were significantly higher in rachitic children than in nonrachitic children. The children with rickets spent a significantly shorter average duration (26.86 minutes ± 19.94) under the sun than those without rickets (30.59 minutes ± 15.72; P < .001). A significantly larger proportion of rachitic children was afflicted with vitamin D deficiency (75.2% versus 62.2%; P < .001), secondary hypothyroidism (100% versus 7.5%; P = .009) and muscular weakness (56.6% versus 26.3%; P < .001). Conclusion. The most important risk factors were low vitamin D and calcium intakes, lack of exposure to sunlight, prolonged breast feeding without supplementation of vitamin D. Hindawi Publishing Corporation 2010 2010-10-27 /pmc/articles/PMC2965426/ /pubmed/21048925 http://dx.doi.org/10.1155/2010/410502 Text en Copyright © 2010 A. Bener and G. F. Hoffmann. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Bener, Abdulbari
Hoffmann, Georg F.
Nutritional Rickets among Children in a Sun Rich Country
title Nutritional Rickets among Children in a Sun Rich Country
title_full Nutritional Rickets among Children in a Sun Rich Country
title_fullStr Nutritional Rickets among Children in a Sun Rich Country
title_full_unstemmed Nutritional Rickets among Children in a Sun Rich Country
title_short Nutritional Rickets among Children in a Sun Rich Country
title_sort nutritional rickets among children in a sun rich country
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965426/
https://www.ncbi.nlm.nih.gov/pubmed/21048925
http://dx.doi.org/10.1155/2010/410502
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